Simvastatin is often a hypolipidemic 61 Pictures Of Drug Disease, and therefore it reduces the degree of lipids inside the blood by up to 1 / 2. Its most frequent use is the treatment of hypercholesterolemia, commonly known as high-cholesterol. Simvastatin is one of the statin class of medicine, such as all kinds of other drugs that treat high cholesterol levels. This drug is primarily sold underneath the name Zocor within the United States which is conveniently obtainable in generic form.
The primary advantage of cutting your cholesterol level will be the decline in your likelihood of heart problems. Physicians should recommend simvastatin only after other traditional measures to lessen cholesterol have failed. These measures include fat loss, exercise and dieting.
Common negative effects of simvastatin are the types effects that appear in more than one percent of cases. These include these:
Rare unwanted effects of simvastatin that occur in under one percent of cases include these:
Researchers could have identified the genes that make individuals at risk of muscle weakness when taking simvastatin. A 2008 study of 32,000 subjects concluded that a definite allele boosts the likelihood of muscle weakness from simvastatin by a factor of 16. Another allele increases this risk by a factor of five.
The doses of simvastatin cover anything from 5 mg to 80 mg. A double-blind controlled study conducted in 2010 showed that patients taking 80 mg daily had 1.2 percent fewer major cardiovascular events than these taking 20 mg each day. The Food and Drug Administration recommends the maximum dosage of 80 mg simply for those patients who've been using this dosage for at least 12 months without muscle weakness. Dosages as much as 160 mg are already found in numerous studies, but this a higher level simvastatin provides only limited additional benefits using a high rate of unwanted effects.
Merck and Co. markets simvastatin within the brand names Zocor and Zocor Heart Pro. This company also sells a mix of simvastatin and ezetimibe underneath the name Vytorin. Brand names for simvastatin in Australia include Simvahexal, Lipex and Zimstat. Simvastatin is also sold as Simcard, Simlup and Simvotin in India. European manufacturers for simvastatin include Denan, Liponorm, Sinvacor, Sivastin and Zocord.
Many other statins are for sale to the treatment of high cholesterol levels. The best-selling drug of the type is atorvastatin, which is sold underneath the brandnames Lipitor and Torvast. Atorvastatin may be the best-selling drug in history with sales of $12.4 billion in 2008. Additional statins currently on the market include fluvastatin, which can be sold as Lescol. Lovastatin is sold as Altocor, Altoprev and Mevacor. The brand names for pitavastatin include Livalo and Pitava. Pravastatin is sold as Pravachol, Lipostat and Selektine, and rosuvastatin is sold as Crestor.
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